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Frederick Schatz Selected Research

Uterine Hemorrhage (Uterine Bleeding)

6/2017Thrombin impairs human endometrial endothelial angiogenesis; implications for progestin-only contraceptive-induced abnormal uterine bleeding.
1/2016The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding.
3/2015Mass spectrometry identification of potential mediators of progestin-only contraceptive-induced abnormal uterine bleeding in human endometrial stromal cells.
1/2015Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding.
3/2011Long-term progestin-only contraception in humans versus animal models.
4/2010Long-term progestin contraceptives (LTPOC) induce aberrant angiogenesis, oxidative stress and apoptosis in the guinea pig uterus: A model for abnormal uterine bleeding in humans.
2/2009Decidualized human endometrial stromal cells mediate hemostasis, angiogenesis, and abnormal uterine bleeding.
2/2007The role of decidualization in regulating endometrial hemostasis during the menstrual cycle, gestation, and in pathological states.
9/2006Long-term progestin-only contraceptives result in reduced endometrial blood flow and oxidative stress.
11/2005Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: Evidence of progestogenic effects.
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Frederick Schatz Research Topics

Disease

18Hemorrhage
12/2017 - 09/2002
16Pre-Eclampsia (Preeclampsia)
01/2022 - 02/2006
13Uterine Hemorrhage (Uterine Bleeding)
06/2017 - 09/2002
10Inflammation (Inflammations)
01/2019 - 03/2004
8Infections
01/2022 - 06/2006
7Chorioamnionitis
12/2015 - 09/2005
7Hypoxia (Hypoxemia)
03/2015 - 09/2002
6Endometriosis
01/2021 - 04/2008
6Rupture
01/2020 - 12/2004
5Premature Birth (Birth, Premature)
01/2020 - 02/2008
5Thrombophilia
03/2011 - 02/2007
3Preterm Premature Rupture of the Membranes
01/2020 - 11/2005
3Neoplasms (Cancer)
01/2020 - 02/2010
3Fetal Growth Retardation (Intrauterine Growth Retardation)
11/2015 - 02/2007
3Abruptio Placentae (Placental Abruption)
12/2012 - 09/2005
2Pregnancy Complications
01/2022 - 12/2009
2Ischemia
01/2016 - 03/2004
2Premature Obstetric Labor (Premature Labor)
04/2007 - 06/2006
1COVID-19
01/2022
1Thrombosis (Thrombus)
01/2022
1Cytokine Release Syndrome
01/2022
1Adenomyosis
01/2021
1Spontaneous Abortion (Miscarriage)
11/2015
1Atrophy
05/2015
1Infertility (Sterility)
04/2012
1Macular Degeneration (Age-Related Maculopathy)
02/2010
1Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
12/2009

Drug/Important Bio-Agent (IBA)

25ThrombinFDA Link
01/2020 - 09/2002
18CytokinesIBA
01/2022 - 08/2005
15Progestins (Progestagens)IBA
12/2017 - 09/2002
12Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019 - 08/2005
10Contraceptive Agents (Contraceptives)IBA
06/2017 - 09/2002
9Thromboplastin (Tissue Factor)IBA
01/2020 - 03/2007
8Interleukin-1beta (Interleukin 1 beta)IBA
08/2009 - 02/2006
7Interleukin-8 (Interleukin 8)IBA
01/2018 - 03/2004
5Messenger RNA (mRNA)IBA
02/2016 - 09/2002
5ProgesteroneFDA LinkGeneric
01/2016 - 03/2004
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2009 - 09/2002
4ChemokinesIBA
01/2022 - 11/2010
4Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2020 - 05/2009
4Matrix Metalloproteinases (MMPs)IBA
01/2016 - 04/2007
4Proteins (Proteins, Gene)FDA Link
03/2015 - 09/2002
3Interleukin-11 (Interleukin 11)IBA
01/2022 - 09/2005
3Interleukin-6 (Interleukin 6)IBA
01/2022 - 06/2008
3InterferonsIBA
01/2019 - 09/2014
3Plasminogen Activator Inhibitor 1IBA
01/2016 - 11/2005
3Progesterone Receptors (Progesterone Receptor)IBA
01/2016 - 02/2008
3Reactive Oxygen Species (Oxygen Radicals)IBA
02/2009 - 09/2002
3Hemostatics (Antihemorrhagics)IBA
04/2008 - 08/2005
2EnzymesIBA
01/2021 - 01/2019
2p38 Mitogen-Activated Protein KinasesIBA
01/2021 - 01/2018
2MicroRNAs (MicroRNA)IBA
01/2020 - 02/2016
2Interleukin-1 (Interleukin 1)IBA
01/2019 - 11/2010
2GlucocorticoidsIBA
12/2016 - 01/2015
2Proteinase-Activated ReceptorsIBA
01/2016 - 09/2011
2tiboloneIBA
05/2015 - 11/2005
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
05/2011 - 02/2006
2Angiopoietin-1IBA
02/2009 - 09/2002
2Factor VII (Proconvertin)IBA
02/2009 - 03/2004
2Peptide Hydrolases (Proteases)FDA Link
02/2007 - 11/2005
2Levonorgestrel (Plan B)FDA LinkGeneric
03/2004 - 11/2003
2SteroidsIBA
03/2004 - 09/2002
1Viral RNAIBA
01/2022
12-hydroxyestradiolIBA
01/2021
14-hydroxyestradiolIBA
01/2021
1CollagenIBA
01/2021
1Propranolol (Inderal)FDA LinkGeneric
01/2021
1TamoxifenFDA LinkGeneric
01/2021
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
01/2021
1tizoxanideIBA
12/2020
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2019
1Cell-Free Nucleic AcidsIBA
01/2019
1ImmunosorbentsIBA
01/2019
1LigandsIBA
01/2019
117 alpha-Hydroxyprogesterone Caproate (Delalutin)FDA Link
12/2017
1Biological ProductsIBA
09/2017
1N,N-dimethyl-4-anisidine (DMPA)IBA
06/2017
1Prothrombin (Factor II)IBA
06/2017
1Hormones (Hormone)IBA
12/2016
1Oxidoreductases (Dehydrogenase)IBA
12/2016
1RNA (Ribonucleic Acid)IBA
02/2016
1NucleotidesIBA
02/2016
1ProlactinIBA
05/2015
1Insulin-Like Growth Factor Binding Protein 1IBA
05/2015
1etonogestrel (Implanon)FDA Link
03/2015
1Acetates (Acetic Acid Esters)FDA Link
03/2015
1tacrolimus binding protein 4 (FKBP52)IBA
04/2012
1Metalloproteases (Metalloproteinases)IBA
09/2011
1InterleukinsIBA
03/2011
1Immunoconjugates (Immunoconjugate)IBA
02/2010
1AnticoagulantsIBA
12/2009
1Heparin (Liquaemin)FDA LinkGeneric
12/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2009
1Neuropilin-1IBA
08/2009
1Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
07/2009
1EndoglinIBA
07/2009
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
07/2009

Therapy/Procedure

3Contraception (Birth Control)
03/2011 - 09/2002
3Therapeutics
12/2009 - 11/2005
1Long-Acting Reversible Contraception
01/2016